Compare Villas, Resorts, & Rentals in Otay Mesa, San Diego, California, USA
About Otay Mesa Vacation Rentals
There are more than 30 incredible getaway rentals that are available in Otay Mesa. These choices include villas, hotels, and other rental options. Browse from a massive selection of luxury amenities at great prices, providing you with the dream spot to base your next vacation. Relax with BedroomVillas and uncover great stays in Otay Mesa.
BedroomVillas features numerous last-minute deals on villas, hotels, and rentals, in locations near you or across the globe. If you need a place for a group or event, be it a hotel or vacation rental (as well as cabins and private luxury villas), let us help. With BedroomVillas in Otay Mesa, you can compare options from multiple suppliers with a single click to find the price point, amenities, and style of stay that works for you. Group deals, private pools, hot tubs, allows pets, or even huge master suite bedrooms with open-air showers? You can find it all with the BedroomVillas vacation rentals, resorts, and Airbnb-style properties in Otay Mesa. Places to stay near Otay Mesa are 1146.14 ft² on average, with prices averaging GB £267 a night.
BedroomVillas helps you find the ideal holiday rental to create lifetime travel memories in Otay Mesa. Prices listed are often found to be discounted versus the rack rates. Just search for your destination and secure your perfect place to stay today.
Find Hotels, Resorts, and Rentals Nearby in these Cities & Neighborhoods Otay Mesa, CA
Frequently Asked Questions About Otay Mesa?
What are the top hotels or resorts in Otay Mesa?
- Enjoy San Diego! Less than 5-min drive to Sesame Place and NICU Amphitheater!
- Luxury San Diego Home with Pool, Spa and Views!
- Luxe San Diego Getaway with Pool and Ocean Views
- Luxury San Diego Home w/Pool, Spa & Views!
- Retreat w/EV Charger, Pool, Gym, Workspace + More
- Luxe San Diego Getaway w/Pool & Ocean Views
- Ocean-View San Diego Home with Pool, Patio and Hot Tub
- Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
- Quality Suites San Diego Otay Mesa
- Quality Suites San Diego Otay Mesa
How many hotels, resorts, or rentals are available in Otay Mesa?
BedroomVillas offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by BedroomVillas in 2025 is over 30 in the Otay Mesa area, and that number rises every day. By combining listings from multiple websites and travel providers, BedroomVillas can provide you with a diverse amount of choices of the best luxury stays in Otay Mesa.
Nearby Neighborhood (3)
| Neighborhood | Property Count |
|---|---|
| Otay Ranch Rental Villas and Private Getaways in San Diego, California | 59 |
| Ocean View Hills Rental Villas and Private Getaways in San Diego, California | 110 |
| Princess Park In California Terraces Rental Villas and Private Getaways in San Diego, California | 83 |
